| Autor: |
Snell, Jon, Lillquist, Dean R., Lewis-Younger, Cynthia, Wallace, David O. |
| Zdroj: |
Dermatology; February 2000, Vol. 200 Issue: 2 p124-128, 5p |
| Abstrakt: |
Background:Although effective at treating mycosis fungoides (MF), nitrogen mustard (HN2) creates potential exposure risks to those who administer it, including health care workers and family members. Objective:The main objective was to examine the potential for nontarget individuals to be exposed to HN2 vapors during and shortly after treatment with HN2 in a home environment. Methods:Air concentrations of HN2 were measured during the topical treatment of MF in a patients home. Results:The results demonstrate that eye and mucous membrane irritation may occur at HN2 levels commonly encountered during the treatment of MF in the home, hospital or health clinic. Because no exposure thresholds have been developed for HN2, the exposure thresholds of a surrogate chemical (sulfur mustard) were used. Conclusions:The study findings show that eye and mucous membrane irritation may occur at HN2 levels below the exposure thresholds of the surrogate chemical. Recommendations for controlling exposures to HN2 in the home are given. |
| Databáze: |
Supplemental Index |
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