| Autor: |
Fang, Jing Jing, Liu, An Jun, Zhu, Zhen Yuan, Teng, An Guo, Zheng, Guo Qiang, Wang, Wen Hang, Rong, Qi, Qi, Yu Gang |
| Zdroj: |
Advanced Materials Research; July 2013, Vol. 716 Issue: 1 p451-454, 4p |
| Abstrakt: |
The antitumor activity of porcine cartilage polysaccharide was evaluated by vivo animal models. The Ca761 tumor-bearing mice were treated with daily intraperitoneal injections of normal saline (control group) or cartilage polysaccharide (1500, 3000 or 4500mg/kg CPS group) for 14 days. The results demonstrated that CPS could effectively inhibit the tumor growth in Ca761 tumor-bearing mice. The tumor weights of the CPS groups were smaller compared to the control group. While the thymus index, spleen index were higher in the high dose 4500mg/kg CPS group than the control group. These results suggest that CPS might be a strong natural immunomodulator and the antitumor effect of this polysaccharide is associated with its potent immunostimulating effect. |
| Databáze: |
Supplemental Index |
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