| Autor: |
PATTERSON, K.G., CAWLEY, J.C., GOLDSTONE, A.H., RICHARDS, J.D.M., JANOSSY, G. |
| Zdroj: |
Clinical & Laboratory Haematology; December 1980, Vol. 2 Issue: 4 p281-291, 11p |
| Abstrakt: |
Thirty cases of untreated acute leukaemia were analysed by continuous flow automated cytochemistry on the Hemalog D differential counter, and the results compared with conventional morphological and cytochemical data. The print‐out Hemalog D data were abnormal in 29 of the 30 cases, the most common abnormalities being an increased percentage of large unstained cells and the presence of a low peroxidase alarm; in combination these two abnormalities were virtually diagnostic of acute leukaemia. In 26 of the 30 cases the Hemalog D distinguished acute myeloid leukaemia from acute lymphoblastic leukaemia by virtue of the increased size and variable degrees of peroxidase activity in myeloblasts. Two of the four remaining cases were probably best classified as mixed myeloid‐lymphoid leukaemia, and this was reflected in the Hemalog D analysis. Further subclassification of acute myeloid leukaemia into the morphologically recognized subgroups was possible on the basis of numbers of large unstained cells, peroxidase and esterase activity. The Hemalog D did not distinguish the various forms of acute lymphoblastic leukaemia. |
| Databáze: |
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