akirinis required for diakinesis bivalent structure and synaptonemal complex disassembly at meiotic prophase I

Autor: Clemons, Amy M., Brockway, Heather M., Yin, Yizhi, Kasinathan, Bhavatharini, Butterfield, Yaron S., Jones, Steven J. M., Colaiácovo, Monica P., Smolikove, Sarit
Zdroj: Molecular Biology of the Cell; April 2013, Vol. 24 Issue: 7 p1053-1067, 15p
Abstrakt: Formation of a condensed and properly remodeled bivalent is required for accurate execution of meiosis. Meiotic roles are identified for the highly evolutionarily conserved protein AKIRIN in bivalent remodeling in a synaptonemal complex (SC)–dependent and SC–independent manner, demonstrating that proper SC disassembly is crucial for bivalent structure.
Databáze: Supplemental Index