Office hours pulsed brachytherapy boost in breast cancer

Autor: Sminia, Peter, Schneider, Christoph J, van Tienhoven, Geertjan, Koedooder, Kees, Blank, Leo E.C.M, González González, Dionisio
Zdroj: Radiotherapy and Oncology; June 2001, Vol. 59 Issue: 3 p273-280, 8p
Abstrakt: Background and purpose: Radiobiological studies suggest equivalent biological effects between continuous low dose rate brachytherapy (CLDR) and pulsed brachytherapy (PB) when pulses are applied without interruption every hour. However, radiation protection and institute-specific demands requested the design of a practical PB protocol substituting the CLDR boost in breast cancer patients. An office hours scheme was designed, considering the CLDR dose rate, the overall treatment time, pulse frequency and tissue repair characteristics. Radiobiological details are presented as well as the logistics and technical feasibility of the scheme after treatment of the first 100 patients.
Databáze: Supplemental Index