| Autor: |
Ding, Yi Lin, Ding, Su Su, Ding, Guo Fang |
| Zdroj: |
Advanced Materials Research; December 2012, Vol. 621 Issue: 1 p130-133, 4p |
| Abstrakt: |
Chitosan microspheres were prepared by using a cross linking agent combined with an emulsion technique. Cyclophosphamide was loaded as an anticancer agent. Obtained microspheres were spherical and regular, with a smooth surface morphology, having an average diameter of 15.7±9.0μm. After preparation, the drug-loading rate and entrapment rate of cyclophosphamide was investigated by UV spectrophotometry. Drug release was tested in vitro in a dynamic dialysis system with a dialysis bag. The chitosan microspheres prepared were proved to have good drug release profiles. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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