THE USE OF STANDARDIZED MOUSE BRAIN ANTIGEN: FOR THE PERFORMANCE OF THE FREI TEST FOR LYMPHOGRANULOMA INGUINALE

Autor: GRACE, ARTHUR W., SUSKIND, FLORENCE H.
Zdroj: JAMA: Journal of the American Medical Association; October 1936, Vol. 107 Issue: 17 p1359-1365, 7p
Abstrakt: The recent appearance of an article by Strauss and Howard1 condemning the use of lymphogranulomatous mouse brain antigen for the routine performance of the Frei test has necessitated the publication of our results with the use of this material for a period of two years at the New York Hospital. Since May 1934, 595 tests have been made with mouse brain materials in an attempt to establish the efficacy of lymphogranulomatous mouse brain antigen for Frei testing. The tests included those performed with lymphogranulomatous mouse brain antigen, both our own (New York Hospital) and commercial, in patients infected with lymphogranuloma inguinale and control tests which were carried out with normal mouse brain antigen in the same subjects and with normal mouse brain and lymphogranulomatous mouse brain antigens in individuals who have never had the disease. In Strauss and Howard's paper the only results that are strictly comparable with ours
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