| Abstrakt: |
As early as 1931 Kracke1 reported severe and repeated attacks of agranulocytosis in an individual using large amounts of coal tar derivatives. He likewise suggested that the benzene chain contained in the drugs might act as a powerful leukocytic depressant. More recently, he2 has called particular attention to this fact in a review of nine cases. Madison and Squier3 directly accuse certain of the benzene derivatives as causative factors of granulopenia in a large number of cases.The following case is reported because it adds to the evidence that severe granulopenia may follow the administration of drugs of this group:REPORT OF CASEHistory.—A white woman, aged 48, a nurse, while on duty suddenly experienced the prodromal symptoms of a grippal infection, characterized by headache, chills, exhaustion and sore throat. After two or three days of self medication (?) her condition grew worse and she was admitted |
