TREATMENT OF ACUTE MICROCOCCIC (STREPTOCOCCIC) PHARYNGITIS WITH PENICILLIN

Autor: Feldman, Harry A., Bernstein, Stanley H., Williams, Harold B.
Zdroj: JAMA: Journal of the American Medical Association; May 1954, Vol. 155 Issue: 2 p109-111, 3p
Abstrakt: The studies of Massell and others in children1 and Wannamaker and others in military populations2 have demonstrated that early treatment with penicillin of group A micrococcic (streptococcic) infections may prevent both initial and recurrent attacks of acute rheumatic fever. For such treatment to be effective it is necessary that the penicillin, whether orally or parenterally administered, be given long enough for clinical and bacteriological relapses to be prevented, for these relapses may be followed by rheumatic fever as well as by untreated micrococcic pharyngitis. Although treatment for micrococcic pharyngitis may be instituted soon enough with either multiple injections or tablets given orally or a combination of these, in many instances such therapy ultimately proves inadequate because it is discontinued too early. The relapse that then may occur may be clinically mild or purely bacteriological, and the patient is subject to the complications of micrococcic disease, with his associates
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