| Autor: |
Hasen, Howard B., Moore, Thomas D. |
| Zdroj: |
JAMA: Journal of the American Medical Association; August 1954, Vol. 155 Issue: 17 p1470-1473, 4p |
| Abstrakt: |
During World War II, the need for new antibacterial drugs became paramount when the sulfonamides and antibiotics failed to control all the infections encountered. Millions of dollars and man-hours were spent in the search for new drugs. Most of these proved to be either worthless in the treatment of infections in man or too toxic to be really beneficial; however, remarkable advances were made with the discovery of several useful agents, each of which has a place in the modern armamentarium of antibacterial therapeutics. Several groups of scientists have worked in the relatively new field of antibiotics, while others have continued with the older concept of control of disease by chemical means. In the latter group are Dodd and Stillman,1 who in 1944 found that the addition of a 5-nitro group to the furan ring conferred considerable bacteriostatic action on the derivative. From these investigations the preparation nitrofurazone2 |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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