| Autor: |
Salassa, Robert M., Bennett, Warren A., Keating, F. Raymond, Sprague, Randall G. |
| Zdroj: |
JAMA: Journal of the American Medical Association; August 1953, Vol. 152 Issue: 16 p1509-1515, 7p |
| Abstrakt: |
Although therapeutic experience with cortisone has been accumulated rapidly during the past four years, the limits of therapeutic usefulness and the hazards of this and similar compounds still await precise definition. There is considerable evidence to support the view that the administration of adrenal cortical hormones may suppress adrenal function and induce adrenal atrophy. The extent, duration, and potential seriousness of this hazard in medical and surgical practice are, however, only now becoming apparent. A year ago, Fraser and co-workers1 reported a postoperative death that was regarded as the result of acute postoperative adrenal cortical insufficiency associated with atrophy and functional suppression of the adrenal cortex induced by previous treatment with cortisone. We wish to describe two additional examples of the same surgical complication, with further observations on the occurrence in man of adrenal atrophy induced by cortisone. REPORT OF CASES CASE 1. *—A woman, 54 years of age, |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
|
