Autor: |
DAVIS, LOYAL, MARTIN, JOHN, ASHKENAZY, MOSES, LeROY, GEORGE V., FIELDS, THEODORE |
Zdroj: |
JAMA: Journal of the American Medical Association; December 1950, Vol. 144 Issue: 17 p1424-1432, 9p |
Abstrakt: |
Radioactive diiodofluorescein has been utilized in the study of 200 patients with the diagnosis of a space-occupying lesion of the central nervous system. We have correlated our observations with the preoperative clinical diagnosis, electroencephalography, pneumography, angiography and surgical and autopsy observations. We have made postoperative and postirradiation tests and, finally, we have correlated all these studies with the histopathological characteristics of the tumors. The results indicate that this radioactive isotope dye test is a valuable diagnostic adjunct in neurosurgical problems not only because of its high degree of accuracy in determining the presence of brain tumors but also because of its relatively precise focal localization. The possibility of prognosticating in a general fashion the relative degree of cellularity and vascularity of the tumor also appears to be feasible.Fluorescein was believed to have a special affinity for tumor cells as early as 1911, at which time Wasserman, Keysser and Wasserman |
Databáze: |
Supplemental Index |
Externí odkaz: |
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