EFFECT OF ACTH ON CERTAIN INFLAMMATORY DISEASES OF THE EYE: A Preliminary Report

Autor: OLSON, JAMES A., STEFFENSEN, E. H., MARGULIS, R. R., SMITH, RICHMOND W., WHITNEY, E. L.
Zdroj: JAMA: Journal of the American Medical Association; April 1950, Vol. 142 Issue: 16 p1276-1278, 3p
Abstrakt: The current investigation, with which this preliminary report is concerned in part, was motivated by several considerations. First, artificially induced fever used in the treatment of many of the inflammatory disorders of the eye frequently may achieve the desired effect by the acceleration of the mechanisms normally evoked in many stress states. In this regard, the results of recent laboratory and clinical research are such as to ascribe a basic role to the adrenal gland. Second, the eye is particularly suited, as is no other organ, for direct and minute visualization of disease processes. Here the vascular, cellular and exudative changes of both primary and secondary disease can be observed. In a sense, this opportunity may be considered comparable to that which Markee1 recognized when he visualized the hormonal response of endometrial tissue implanted in the anterior chamber of the monkey's eye. Thus, to be able to directly observe
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