Autor: |
SACKS, MILTON S., JAHN, ELSA F., KUHNS, WILLIAM J. |
Zdroj: |
JAMA: Journal of the American Medical Association; December 1946, Vol. 132 Issue: 16 p983-985, 3p |
Abstrakt: |
Subsequent to the initial report in 19401 of the discovery of the Rh factor in human red blood cells there has been a rapid succession of papers emphasizing the importance of this new knowledge to clinical medicine. The principal applications have been to certain problems of obstetrics and pediatrics and to transfusion therapy. Rh testing and studies of Rh isoimmunization, however, did not become widespread immediately for a variety of reasons. Among these may be mentioned the relative scarcity and expense of potent and reliable testing serums; the increasing antigenic complexity of the Rh factor, and technical problems associated with the demonstration of anti-Rh immune bodies. Sporadic studies were made in some obstetric patients whose previous histories were strongly suggestive of the effects of Rh incompatibility and in other persons in whom, in the course of receiving multiple transfusions, inexplicable reactions developed. As it became increasingly obvious that varying |
Databáze: |
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Externí odkaz: |
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