| Autor: |
Greenwald, Louis, Litwins, Joseph, Spielholz, Jess B. |
| Zdroj: |
JAMA: Journal of the American Medical Association; March 1942, Vol. 118 Issue: 12 p975-977, 3p |
| Abstrakt: |
An extensive literature has accumulated1 reporting the toxic effects of sulfanilamide on the blood forming organs. These reactions consist of acute hemolytic anemia with leukocytosis, occasionally a leukemoid blood picture,2 severe leukopenia with granulocytopenia and thrombopenia with hemorrhagic phenomena. Such deviations may occur singly or in combination. The outcome occasionally has been fatal.3 The cases reported up to the present time usually have presented initially a normal hemoglobin and red cell count or slightly diminished values. A careful search of the literature fails to disclose any reference to a case of polycythemia vera in which there was a toxic reaction of the blood in the course of the administration of sulfanilamide. The following is the report of a case of polycythemia vera and prostatic infection in which anemia, severe leukopenia and neutropenia developed as the result of the administration of sulfanilamide.A white man aged 61, born |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
|
