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To the Editor:—In The Journal, February 8, there appeared the report of a case of scleroderma with pulmonary fibrosis by Drs. Murphy, Krainin and Gerson of New York in which they draw attention to the fact that the pathologic changes in scleroderma are not confined to the skin and subcutaneous tissue alone but may involve the connective tissue system throughout the entire body. Their case presented pulmonary fibrosis or sclerosis as a clinical manifestation of the disease.The authors state that "a search of the literature of scleroderma has brought to light no other case in which the pulmonary manifestations of the disease were visualized by roentgenographic study." However, in the New England Journal of Medicine (216:188 [Jan. 28] 1937) Dr. Harry Linenthal of Boston reported two cases in which pulmonary fibrosis occurred associated with Raynaud's disease and scleroderma. Dr. Linenthal concluded that changes in the pulmonary arterial |
