A Pattern of Structural Change in Liver Autotransplantation: An Experimental Study in Dogs

Autor: Sigel, Bernard, Dunn, Marvin R., Puente-Duany, G. A.
Zdroj: JAMA: Journal of the American Medical Association; November 1961, Vol. 178 Issue: 5 p483-486, 4p
Abstrakt: LIVER AUTOTRANSPLANTATION is the surgical removal of hepatic tissue from its natural site and relocation within the same subject. Further, as suggested by Dempster,1 autotransplantation entails the transfer of tissue without significant interruption of its blood supply, thus assuring a maximal survival of cells. This definition distinguishes transplantation from implantation. Implantation is the transfer of free fragments of tissue without provision for a continuity of the vascular supply, resulting initially in varying degrees of necrosis.The lack of a clear distinction between auto-transplantation and autoimplantation and a scarcity of long-term observations of either method of liver tissue transfer has resulted in incomplete and sometimes confusing descriptions of the morphology of liver autotransplants. A study which would add such information would, therefore, be of importance, particularly in 2 respects: (1) to enhance the understanding of the general transplantation phenomenon by delineating what anatomical changes may be inherent to transplantation per
Databáze: Supplemental Index