| Autor: |
Crandell, D. LeRoy, Whitcher, Charles E. |
| Zdroj: |
JAMA: Journal of the American Medical Association; January 1960, Vol. 172 Issue: 1 p15-19, 5p |
| Abstrakt: |
To arrest the progress of tetanus in a patient two main objectives must be attained, namely, the neutralization of circulating toxin and the elimination of its source. Meanwhile the neuromuscular manifestations must be controlled. Drugs used for this purpose are generally depressants of the central nervous system. If they hamper cardiovascular and respiratory function their use is illogical. The regimen advised by the authors employs a sedative (either secobarbital or pentobarbital) and a muscle relaxant (methocarbamol) together with chlorpromazine, which is believed to potentiate the sedative-relaxant effects of the other two drugs. Strict attention to pulmonary ventilation is essential. Tracheotomy should be performed early in severe cases. The aspiration of tracheobronchial secretions must be prevented, and it may be necessary to assist respiration by mechanical means. In the prevention of asphyxia the anesthesiologist can play a vital role. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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