Metastatic Melanoma to the Cerebellopontine Angle: Clinical and Imaging Characteristics

Autor: Arriaga, Moises A., Lo, William W. M., Brackmann, Derald E.
Zdroj: Archives of Otolaryngology-Head & Neck Surgery; September 1995, Vol. 121 Issue: 9 p1052-1056, 5p
Abstrakt: OBJECTIVE: To describe the clinical and imaging features of metastatic melanoma to the cerebellopontine angle (CPA). DESIGN: A case series study with world literature review. SETTING: House Ear Clinic and St Vincent's Hospital, Los Angeles, Calif. PATIENTS: Three cases of metastatic CPA tumors operated on at the House Ear Clinic. INTERVENTIONS: All patients underwent surgical removal of CPA metastatic melanoma. MAIN OUTCOME MEASURE: Survival and duration of disease-free interval are reported. RESULTS: Two patients died of melanoma within 5 months of diagnosis and resection of CPA melanoma metastases. One patient survived for 5 years after undergoing total resection of an isolated CPA melanoma metastasis. Magnetic resonance imaging features were not uniform. CONCLUSIONS: Metastatic melanoma to the CPA should be suspected in patients with a history of melanoma and a rapid progression of audiovestibular or facial nerve symptoms. Surgical removal of solitary metastases to the CPA may be valuable in patients without other melanoma focus; however, the longterm prognosis for patients with CPA melanoma is grim.(Arch Otolaryngol Head Neck Surg. 1995;121:1052-1056)
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