Cisplatin Potentiation of Radiotherapy: Long-term Follow-up

Autor: Leipzig, Bruce, Wetmore, Stephen J., Putzeys, Roberto, Suen, James Y., Snyderman, Nancy L.
Zdroj: Archives of Otolaryngology-Head & Neck Surgery; February 1985, Vol. 111 Issue: 2 p114-118, 5p
Abstrakt: • Thirty-three patients with inoperable squamous cell carcinoma of the head and neck were treated with cisplatin, 15 mg/sq m, administered synchronously with high-dose radiation therapy. Twenty-nine patients (88%) responded to the regimen; of these, 20 had complete regression of all disease. Eight of the 20 had a relapse in less than one year of their treatment. Among those patients who did not have a relapse, the follow-up period was short. It is concluded that a clinical regression response is more likely with this treatment regimen than with radiation therapy alone, and that that response may be a better palliation. Further study of this combination of treatment modalities is warranted.(Arch Otolaryngol 1985;111:114-118)
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