Autor: |
Finger, Paul T., Packer, Samuel, Svitra, Paul P., Paglione, Robert W., Chess, Jeremy, Albert, Daniel M. |
Zdroj: |
Archives of Ophthalmology; October 1984, Vol. 102 Issue: 10 p1477-1481, 5p |
Abstrakt: |
• A 5.8-gigahertz (GHz) ophthalmic microwave applicator was used to treat choroidal melanoma (Greene strain) in rabbits. High-frequency electromagnetic radiation provides a favorable dose distribution to induce local hyperthermia in the treatment of intraocular tumors. Heating of the neoplasm, while sparing normal ocular structures, is best accomplished by a transscleral approach. A hyperthermia plaque is placed on the sclera at the base of the intraocular tumor. Contact (resistive) heating and electromagnetic radiation (radiofrequency and microwave) are best suited to a plaque technique. The advantages of electromagnetic heat induction, as compared with contact heating, are twofold: the depth of hyperthermic penetration can be modulated by frequency selection, and the tissues with low water content (sclera) remain relatively unaffected by microwaves. The 5.8-GHz ophthalmic microwave applicator satisfies the requirements for local hyperthermic treatment of intraocular tumors. |
Databáze: |
Supplemental Index |
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