Intravitreal Amphotericin B Treatment of Candida Endophthalmitis

Autor: Stern, George A., Fetkenhour, Carl L., O'Grady, Richard B.
Zdroj: Archives of Ophthalmology; January 1977, Vol. 95 Issue: 1 p89-93, 5p
Abstrakt: • A 43-year-old heroin addict with Candida albicans endophthalmitis was treated with a single 5-μg intravitreal injection of amphotericin B. The diagnosis was confirmed by smears and cultures of a vitreous aspiration. The patient's accidental death seven weeks after treatment enabled us to obtain histopathologic evidence that the infection had been cured and that the amphotericin B had had no toxic effect on the retina. Intravitreal amphotericin B should be considered an important mode of treatment of Candida endophthalmitis.(Arch Ophthalmol 95:89-93, 1977)
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