| Autor: |
Misery, Laurent, Guyotat, Denis, Boucheron, Simone, Claudy, Alain |
| Zdroj: |
Archives of Dermatology; July 1996, Vol. 132 Issue: 7 p832-832, 1p |
| Abstrakt: |
In a recent study, Aractingi et al1 reported on 8 cases of neutrophilic dermatoses occurring during granulocytopenia. Although the role of neutrophils seems to be important in these diseases, the pathogeny is not well known. The involvement of other cell lineages is probable. In their study, Aractingi et al showed that neutrophilic dermatoses occurring during granulocytopenia are more frequently found in patients with French-American-British acute myeloid leukemia subtypes 4 and 5 (AML4 and AML5), ie, myelomonocytic and monocytic leukemias. Aractingi et al hypothesized that the neutrophils in the dermal infiltrate derived from differentiated leukemic cells. Both AML4 and AML5 are mainly related to malignant proliferation of monocytoid cells.2Several works are in favor of the prominent role of dermal dendrocytes in the physiopathogeny of Sweet syndrome and other neutrophilic dermatoses.3-5 Jordaan3 showed that neutrophilic dermatoses pass through lymphocytic, neutrophilic, and histiocytic stages. Neutrophils are not necessarily |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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