| Autor: |
Amon, Robert B., Dimond, Robert L. |
| Zdroj: |
Archives of Dermatology; November 1975, Vol. 111 Issue: 11 p1433-1437, 5p |
| Abstrakt: |
• Based on the difference in the level of epidermal split, staphylococcal-induced toxic epidermal necrolysis (TEN) can be rapidly differentiated from drug-induced TEN. The microscopic pathologic findings of the staphylococcal-induced disease shows epidermal cleavage high in the malpighian layer, while the non-staphylococcal-induced disease shows a subepidermal split. Rapid differentiation is accomplished by histologically examining a frozen section of peeled skin obtained from a fresh lesion of TEN and by performing a Tzanck preparation on the denuded base.In order to illustrate these techniques, we present the cases of two adult patients with TEN; in one the disease was staphylococcal-induced while in the other it was drug-induced.(Arch Dermatol 111:1433-1437, 1975) |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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