| Abstrakt: |
A slowly progressive disease characterized clinically by a noninflammatory process, produced over many years unique annular atrophic disfiguring plaques of the face in two patients.The histopathological findings of many lesions revealed sclerosis and fibrosis of the upper and middle dermis, mild lymphocytic inflammation, and atrophy of the epidermis and hair follicles. Severe solar elastosis was a prominent feature in most biopsies and may be an important factor.No evidence of photosensitivity, porphyria, cicatricial pemphigoid, lichen planus, or any significant systemic disease was present. The disease did not respond to corticosteroids, antimalarials, or many other forms of therapy.Many consultants in pathology suggested various diagnoses: morphea, lichen sclerosus et atrophicus, and discoid lupus erythematosus. |
