Abstrakt: |
One case of allergic urticaria has been reported resulting from sensitivity to the suspending agents in the aqueous vehicle of hydrocortisone suspension.* The specific incriminating allergen apparently was not determined.To our knowledge, therefore, the following case is the first to be reported in which a specific component of the hydrocortisone vehicle has been shown to provoke a systemic cutaneous allergic reaction.Report of a CaseA white woman, aged 47, was seen in our office on Sept. 2, 1954, at which time 0.2 cc. of hydrocortisone (Merck's Hydrocortone suspension) was injected into and beneath a synovial cyst of the right fourth finger. Several additional injections were made at two- to three-week intervals, and, according to the patient, after each injection, with the exception of the first, she experienced an extensive hemorrhagic eruption.We were able to reproduce the eruption |