| Abstrakt: |
Every serologist has seen the occasional phenomenon during the routine performance of the standard Kahn test of the serum which gives an atypical or reverse reaction, i. e., decided flocculation in the first tube, falling off to a weaker reaction in the middle and back tubes. Such results are relatively unusual1; of 15,105 specimens of blood examined routinely in the laboratory, 122 gave reverse reactions, or well under 1 per cent. These reactions are sufficiently unusual to cause comment from the recently initiated. The theory of these atypical reactions is based on the fact that the flocculation procedure is essentially a process of adsorption. The reaction of a specific serum is dependent on the ratio of reagin to antigen. In a 4-4-4 reaction there is sufficient reagin to produce flocculation in each tube. In a 1-2-4 reaction the reagin is potent enough to react strongly with the amount of |
