New fascaplysin-based CDK4-specific inhibitors: design, synthesis and biological activity
| Autor: | Aubry, Carine, Jenkins, Paul R., Mahale, Sachin, Chaudhuri, Bhabatosh, Maréchal, Jean-Didier, Sutcliffe, Michael J. |
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| Zdroj: | Chemical Communications; 2004, Vol. 2004 Issue: 15 p1696-1697, 2p |
| Abstrakt: | The first biologically active non-planar analogues of the toxic anti-cancer agent, fascaplysin, have been produced; we present the design, synthesis and biological activity of three tryptamine derivatives. |
| Databáze: | Supplemental Index |
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