Spray-applied cell therapy with human allogeneic fibroblasts and keratinocytes for the treatment of chronic venous leg ulcers: a phase 2, multicentre, double-blind, randomised, placebo-controlled trial

Autor: Kirsner, Robert S, Marston, William A, Snyder, Robert J, Lee, Tommy D, Cargill, D Innes, Slade, Herbert B
Zdroj: The Lancet; September 2012, Vol. 380 Issue: 9846 p977-985, 9p
Abstrakt: Many patients with venous leg ulcers do not heal with standard care. HP802-247 is a novel spray-applied cell therapy containing growth-arrested allogeneic neonatal keratinocytes and fibroblasts. We compared different cell concentrations and dosing frequencies of HP802-247 for benefit and harm when applied to chronic venous leg ulcers.
Databáze: Supplemental Index