Antimicrobial Activity and Cytotoxicity Evaluation of Euphorbia hirta(L.) Extracts from Malaysia

Autor: Perumal, Shanmugapriya, Mahmud, Roziahanim, Pillai, Suthagar, Lee, Wei Cai, Ramanathan, Surash
Zdroj: APCBEE Procedia; January 2012, Vol. 2 Issue: 1 p80-85, 6p
Abstrakt: The present study was aimed at evaluating the antimicrobial and cytotoxic activities of various extracts of Euphorbia hirta. The ethanolic extract exhibited the strongest antimicrobial activity against Salmonella typhiwith MIC value of 0.031mg/ml. In contrast, hexane extract appeared to be the least active extract as its inhibition potency was been observed only on Proteus vulgaris. Dichloromethane and ethyl acetate extracts demonstrated moderate activities with MIC values in the range between 1- 0.5mg/ml. Interestingly, all the extracts exhibited no cytotoxic effect against Vero cell line. The results showed E.hirtaextracts possess promising antimicrobial properties.
Databáze: Supplemental Index