CYP2D6 Inhibition by Selective Serotonin Reuptake Inhibitors: Analysis of Achievable Steady‐State Plasma Concentrations and the Effect of Ultrarapid Metabolism at CYP2D6

Autor: Lam, Y. W. Francis, Gaedigk, Andrea, Ereshefsky, Larry, Alfaro, Cara L., Simpson, Joe
Zdroj: Pharmacotherapy; August 2002, Vol. 22 Issue: 8 p1001-1006, 6p
Abstrakt: Study Objective.To assess the correlation between plasma concentrations of four commonly administered selective serotonin reuptake inhibitors (SSRIs) and the magnitude of cytochrome P450 (CYP) 2D6 inhibition.
Databáze: Supplemental Index