A Multicenter Evaluation of Gentamicin Therapy in the Neonatal Intensive Care Unit

Autor: Glover, Mark L., Shaffer, Christopher L., Rubino, Christopher M., Cuthrell, Corey, Schoening, Shellie, Cole, Erika, Potter, David, Ransom, J. Laurence, Gal, Peter
Zdroj: Pharmacotherapy; January 2001, Vol. 21 Issue: 1 p7-10, 4p
Abstrakt: Study Objective. To evaluate traditional nomogram (TN) versus individualized pharmacokinetic gentamicin dosing practices in neonatal intensive care units, focusing on achieving target therapeutic concentrations (peak > 8 μg/ml, trough < 2 μg/ml), number of dosing changes, number of concentrations obtained, and evidence of nephrotoxicity.
Databáze: Supplemental Index