A Dose‐Escalation Study of the Safety, Tolerability, and Pharmacokinetics of Intravenous Gatifloxacin in Healthy Adult Men

Autor: Gajjar, Diptee A., LaCreta, Frank P., Uderman, Howard D., Kollia, Georgia D., Duncan, Glenn, Birkhofer, Martin J., Grasela, Dennis M.
Zdroj: Pharmacotherapy; October 2000, Vol. 20 Issue: 2 p49S-58S, 10p
Abstrakt: Study Objectives.To examine single‐ and multiple‐dose safety, tolerability and pharmacokinetics of gatifloxacin administered as daily 1‐hour intravenous infusions for 14 days, and to determine the effect of gatifloxacin on glucose tolerance, pancreatic β‐cell function, and electrocardiogram (ECG).
Databáze: Supplemental Index