| Autor: |
Wataha, John C., Ratanasathien, Somjin, Hanks, Carl T., Sun, Zhilin |
| Zdroj: |
Dental Materials; September 1996, Vol. 12 Issue: 5-6 p322-327, 6p |
| Abstrakt: |
Objectives. Previous studies have shown that biomaterials can activate macrophages to produce cytokines and promote an inflammatory response. Although the toxicity of many metal ions has been extensively investigated, little is known about the ability of these ions to alter cytokine release from macrophages. Yet the release of these ions from biomaterials has been well documented. Previous studies indicated that alterations in cytokine release might be expected because metal ions alter protein production in macrophages at sub-toxic concentrations. Thus, the hypothesis of this study was that metal ions can alter the secretion of cytokines from macrophages at sub-toxic concentrations. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
|
Full Text from ScienceDirect