| Autor: |
Teckchandani, Anjali, Mulkearns, Erin E., Randolph, Timothy W., Toida, Natalie, Cooper, Jonathan A. |
| Zdroj: |
Molecular Biology of the Cell; August 2012, Vol. 23 Issue: 15 p2905-2916, 12p |
| Abstrakt: |
Dab2 binds EH domain proteins. This interaction is required for integrin ß1 but not TfnR endocytosis. ß1 and TfnR do not colocalize, even though their adaptors sort to the same pits. The data suggest that Dab2 selectively drives ß1 endocytosis. It is proposed that specific cargo–adaptor–EH domain protein complexes are needed for efficient endocytosis. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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