| Autor: |
HURLEY, JOHN D., WILSON, STUART D., WORMAN, LEONARD W., CAREY, LARRY C. |
| Zdroj: |
Archives of Surgery; April 1966, Vol. 92 Issue: 4 p548-553, 6p |
| Abstrakt: |
REGIONAL perfusion, first described by Creech and co-workers in 1958,1 with cancer chemotherapeutic agents for neoplastic diseases is a method of delivering to the area of disease, a concentration of the antineoplastic drug that would not ordinarily be tolerated systemically as well as delivering a significantly greater concentration of the drug per unit weight of tumor. A similar technique using antibiotics was also described by Ryan et al2,3,4 and has been explored and evaluated over the past six years in our clinic. A number of clever and seemingly useful modifications of the regional approach to treatment have been discussed and described (antitoxin perfusions for snake bite; antifungal perfusion for localized fungus disease [coccidioidomycosis and blastomycosis]) since the application of the extracorporeal pump circuit was first describedThe perfusion method of treatment for osteomyelitis is an obvious choice to be explored since the disease represents a localized involvement of |
| Databáze: |
Supplemental Index |
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