| Autor: |
van Heerden, Jonathan A., Weiland, Louis H., ReMine, William H., Walls, Joseph T., Purnell, Don C. |
| Zdroj: |
Archives of Surgery; April 1979, Vol. 114 Issue: 4 p475-480, 6p |
| Abstrakt: |
• Hyperfunctioning parathyroid carcinoma is a relatively rare endocrine tumor, accounting for approximately 1% of all cases of primary hyperparathyroidism. The diagnosis is suspected when the tumor is large, parathyroid hormone (iPTH) levels are high, and a palpable tumor is present in the neck. Patients who have recurrence of hyperparathyroidism several months after surgical treatment should be suspected of having a recurrent or persistent parathyroid carcinoma. At operation, a large invasive tumor is usually found. The fibrous, inflammatory-like reaction is the most characteristic indication of malignancy. Even in tumors with minimal invasiveness, the possibility of a carcinoma should be considered if the tumor has mitotic activity and a monotonous instead of a pleomorphic cellular population. If the surgeon can recognize the possibility of parathyroid malignancy and adequately treat the patient during the initial operation, more gratifying results should be obtained.(Arch Surg 114:475-480, 1979) |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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