| Autor: |
Gissen, Aaron J., Karis, Johannes H., Nastuk, William L. |
| Zdroj: |
JAMA: Journal of the American Medical Association; September 1966, Vol. 197 Issue: 10 p770-774, 5p |
| Abstrakt: |
The patient with impaired muscle function presents a special problem to the anesthesiologist. At the end of general anesthesia, muscular relaxation must be reversed as quickly and as completely as possible, and for this reason halothane has been a frequent choice as the inhalational anesthetic. Two recent studies1,2 would seem to support this choice since in these experiments the neurally evoked muscle twitch showed no depression during halothane anesthesia. However, in the report by Watland1 it is apparent that the intensity and duration of block by tubocurarine was increased in the presence of halothane anesthesia. Since normal neuromuscular transmission has a reserve safety factor several times that necessary for transmission, a moderate neuromuscular blocking action of halothane might be undetected in twitch tension experiments. This degree of block might be of little consequence under ordinary circumstances, but a moderate blocking action of halothane could be of clinical significance |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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