| Autor: |
Jaffe, Jerome H., Senay, Edward C., Schuster, Charles R., Renault, Pierre R., Smith, Beth, DiMenza, Salvatore |
| Zdroj: |
JAMA: Journal of the American Medical Association; October 1972, Vol. 222 Issue: 4 p437-442, 6p |
| Abstrakt: |
Thirty-four long-term heroin addicts were treated with either methadone hydrochloride or methadyl acetate (dl-methadyl acetate, acetylmethadol) under double-blind conditions over 15 weeks. These drugs were not found to be significantly different with regard to acceptability to patients, reduction of illicit drug use, increase in legitimate employment, reduction of criminal activity, frequency of clinic attendance, and medical safety. These results suggest that the advantages of methadyl acetate, namely reduction in the frequency of clinic visits and the possibility of more effective control over administration and illegal redistribution, are not outweighed by any problems detectable under the conditions of the present study. However, in spite of these potential advantages, the unusual pharmacological actions of methadyl acetate could represent potential hazards. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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