| Autor: |
Woods, John E., Anderson, Carl F., DeWeerd, James H., Johnson, William J., Donadio, James V., Leary, Frank J., Frohnert, Peter P. |
| Zdroj: |
JAMA: Journal of the American Medical Association; February 1973, Vol. 223 Issue: 8 p896-899, 4p |
| Abstrakt: |
Large doses of methylprednisolone were used intravenously as the sole steroid agent in 44 transplants in 43 renal allografted patients for the first two to three weeks after operation and for all episodes of rejection. Orally administered steroids were used only at uniformly low dosage. Although significant rejection episodes occurred, they were almost universally reversible when methylprednisolone was administered intravenously in high doses, the exceptions being the hyperacute responses. The use of this drug form was associated with minimal stigmata of hypercorticism and a low incidence of complications, despite transplantation in high-risk patients. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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