| Autor: |
Serdula, Mary K., Halstead, Scott B., Wiebenga, Ned H., Herrmann, Kenneth L. |
| Zdroj: |
JAMA: Journal of the American Medical Association; April 1984, Vol. 251 Issue: 15 p1974-1977, 4p |
| Abstrakt: |
To document the serological response, 21 seronegative rubella vaccinees (hemagglutination inhibition [HI] titer <10) were revaccinated with RA 27/3 rubella vaccine. All demonstrated an anamnestic response. Although RA 27/3 vaccine was an effective booster, antibody boost was not maintained in some persons. Of 15 persons tested, 24 to 27 months after revaccination, six had a significant HI antibody drop (fourfold or greater); only one had lost all detectable HI antibody. Although all 21 study participants were initially HI seronegative by rubella HI testing, 16 (76.2%) possessed neutralization and/or enzyme-linked immunosorbent assay antibodies before revaccination. As more persons with vaccine-induced immunity join the adult population pool, more sensitive test methods may be needed to assess serological status accurately.(JAMA 1984;251:1974-1977) |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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