| Autor: |
Jasty, V., Kowalski, R., Fonseca, E., Porter, M., Clemens, G., Bare, J., Hartnagel, R. |
| Zdroj: |
Veterinary Pathology; January 1984, Vol. 21 Issue: 1 p46-50, 5p |
| Abstrakt: |
Histologic, histochemical, and electron microscopic studies of generalized ceroid-lipofuscinosis in a cynomolgus monkey are presented. Histologically, a wide variety of tissue cells contained numerous bright eosinophilic intracytoplasmic granules that varied in size from 0.5 μm to 4.0 μm in diameter. Histochemically, the granules gave a weakly positive reaction with periodic acid-Schiff and for lipids. They were weakly acid fast and capable of emitting autofluorescence. Ultrastructurally, the granules were single unit membrane-bound, and contained dense osmiophilic material with frequent concentric or fingerprint-type lamellar formation. The granules were different than hemofuscin, iron, and bilirubin. Tinctorially the granules were unique—they were bright red with hematoxylin and eosin and, thus, differed from typical age-related lipofuscin pigment. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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