Autor: |
Figueiredo, Augusto C. R., dos Santos, Fernanda C. A., Capeletti, Lucas R., Galdino, Marcos V. B., Araújo, Renan V., Marques, Mara R. |
Zdroj: |
Proceedings of SPIE; February 2012, Vol. 8208 Issue: 1 p82080T-82080T-8, 738729p |
Abstrakt: |
Mandibular propulsive appliance (MPA) stimulates cell proliferation and gene expression on mandible condylar cartilage (Marques et al., 2008). However, its association with low level laser therapy (LLLT) is unknown. This study evaluated the effects of LLLT associated to MPA on mandibular condyle. Twenty Wistar rats were divided into four groups. Group I received any treatment. Group II was bilaterally irradiated on temporomandibular joint with 10 J/cm2low level laser (780nm, 40mW and 10s) on alternate days. Group III used the propulsive appliance for ten hours daily and Group IV used the appliance daily and was irradiated on alternate days. After 15 days the animals were killed by lethal doses of anesthetics. The condyles were fixed in Methacarn solution and decalcified in 4.13% EDTA solution for 30 days. Seriate saggital 5 m-thick sections were stained by the hematoxilin-eosin method. Morphological and morphometric analyses were performed to measure the length and the height of the mandibular condyle, the thickness of the condilar cartilage and the bone mass. Results were expressed as mean ± standard deviation (one-way ANOVA, Tukey's post-test.) The appliance increased all measures compared to the control group, except bone mass. Alone, LLLT had no effects on all measures, however, the association of the appliance with the LLLT increased condylar cartilage and bone mass significantly compared to the others groups. These results suggest that LLLT improves the effects of mandibular propulsive appliance in the condylar cartilage growth and formation of bone mass. |
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