| Autor: |
Li, Wei Hong, Guan, Jing, Jing, Miao Lei, Huang, Shu Jie |
| Zdroj: |
Advanced Materials Research; November 2011, Vol. 393 Issue: 1 p324-329, 6p |
| Abstrakt: |
The aim of the study was to investigate the grafting process of β-cyclodextrin onto chitosan fibers via epichlorohydrin as a crosslinking agent. The parameters influencing the efficiency of the grafting reaction were studied by L9 (34) orthogonal test. The amounts of β-cyclodextrin grafting onto the treated fibers were estimated in terms of levofloxacin content. The optimum process was found to be epichlorohydrin 0.64 ml, temperature25℃, post-reaction time 48h, pre-reaction time 4.5h when chitosan fibers were 0.48g. In the case, the inclusion amount of levofloxacin was 1.792mg/g, and the releasing amount was 0.845mg/g at 35℃. The modified and unmodified fibers were characterized by FTIR Spectroscopy , which indicated that β-CD grafted with chitosan fibers were prepared successfully. |
| Databáze: |
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