| Autor: |
Gharbi, Najoua, Somody, Laurence, Fazaaˆ, Saloua El, Kamoun, Abdelaziz, Gauquelin-Koch, Guillemette, Gharib, Claude |
| Zdroj: |
Life Sciences; 1999, Vol. 64 Issue: 25 p2401-2410, 10p |
| Abstrakt: |
We investigated the central and peripheral sympathetic responses to intermittent dehydration in rats. The norepinephrine (NE) turnover, a biochemical index correlated with noradrenergic neuronal activity, was measured. The modification of blood pressure was also determined by telemetry during the different cycles of dehydration. Dehydration caused a decrease of NE turnover in A2, A5 and A6 nuclei and in peripheral organs. The vasopressinergic level of dehydrated rats decreased in hypophysis and hypothalamus, and increased in plasma. A repeated gradual increase of arterial blood pressure during the first three days of dehydration, followed by a sudden drop when the rats were rehydrated on the fourth day was observed. In conclusion, our study revealed an increase in blood pressure and in central sympathetic activity during dehydration. |
| Databáze: |
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