HER2 Testing in Patients With Breast Cancer: Poor Correlation Between Weak Positivity by Immunohistochemistry and Gene Amplification by Fluorescence In Situ Hybridization

Autor: Perez, Edith A., Roche, Patrick C., Jenkins, Robert B., Reynolds, Carol A., Halling, Kevin C., Ingle, James N., Wold, Lester E.
Zdroj: Mayo Clinic Proceedings; February 2002, Vol. 77 Issue: 2 p148-154, 7p
Abstrakt: To evaluate amplification of the HER-2/neugene by fluorescence in situ hybridization (FISH) in tumors with weakly positive (2+) immunohistochemical staining.
Databáze: Supplemental Index