| Autor: |
Lin, C.C., Yen, M.H., Lo, T.S., Lin, C.F. |
| Zdroj: |
Phytomedicine; December 1997, Vol. 4 Issue: 4 p301-308, 8p |
| Abstrakt: |
The pharmacological effects of Boehmeria niveaand B. niveasubsp. nippononiveawere studied against carrageenan-induced paw edema, acetaminophen (APAP) and D-galactosamine (D-GalN) induced hepatotoxicity in rats, respectively. Water extracts of B. niveaand B. niveasubsp. nippononivearoots were found to maintain significant antiinflammatory activity against carrageenan-induced edema. Moreover, the water extracts of B. niveaand B. niveasubsp. nippononiveasignificantly decreased the acute increase in serum GOT and GPT levels caused by APAP and D-GalN-intoxication. The histopathological changes of hepatic lesions caused by these hepatotoxicants were improved by treatment with B. niveaand B. niveasubsp. nippononivea, which were compared with Silymarin as a standard. |
| Databáze: |
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