Mucosal Immunity in the Genital Tract: Prospects for Vaccines Against Sexually Transmitted Diseases—A Review

Autor: Russell, Michael W., Hedges, Spencer R., Wu, Hong‐Yin, Hook, Edward W., Mestecky, Jiri
Zdroj: American Journal of Reproductive Immunology; July 1999, Vol. 42 Issue: 1 p58-63, 6p
Abstrakt: PROBLEM: Consistent with the absence of protective immunity resulting from previous infection with Neisseria gonorrhoeae, the genital mucosal immune response in human gonorrhea is weak: only low levels of immunoglobulin G (IgG) and immunoglobulin A (IgA) antibodies are detectable against gonococci, and inflammatory cytokine responses are poor.
Databáze: Supplemental Index