| Autor: |
Mintz, Gary S., Popma, Jeffrey J., Pichard, Augusto D., Kent, Kenneth M., Satler, Lowell F., Chiu Wong, S., Kleiber, Benjamin, Painter, Jack A., Kehoe, Mary K., Leon, Martin B. |
| Zdroj: |
Journal of the American College of Cardiology; February 1995, Vol. 25 Issue: 2, Number 2 Supplement 1 p197A-198A, 2p |
| Abstrakt: |
Restenosis within tubular-slotted stents is usually treated with repeat PTCA. To understand the mechanisms of lumen enlargement after PTCA of in-stent restenosis, we used quantitative angiography (measurement of % diameter stenosis) and intravascular ultrasound to study 36 restenotic JJIS stents (7 native coronary and 29 vein graft) before and after repeat PTCA. Reference segment and pre- and post-PTCA measurement of external elastic membrane (EEM), stent, and lumen areas were used to calculate (1) plaque area, (2) neointimal hyperplasia (IH) area within the stent (stent—lumen area), (3) % area stenosis of lesion lumen area vs reference lumen area, (4) and % area stenosis of stent area vs reference lumen area.Pre-PTCAPost-PTCAPAngiographic % diameter stenosis63±1917±11<0.0001Reference lumen area (mm2)9.8±3.3Lesion EEM area (mm2)20.8±6.724.4±7.9<0.0001Stent area (mm2)7.4±3.19.9±3.7<0.0001Lesion lumen area (mm2)2.2±1.26.7±2.2<0.0001Lesion plaque area (mm2)18.6±6.518.0±6.7NSIH area within stent (mm2)5.3±3.33.2±2.5<0.0001% Area stenosis lumen vs reference76.1±14.031.0±22.0<0.0001% Area stenosis stent vs reference23.3±26.9-1.9±33.1<0.0001 |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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