Transplantation and preliminary characterisation of lymphocyte surface markers of Abelson virus-induced lymphomas

Autor: SKLAR, MARSHALL D., SHEVACH, ETHAN M., GREEN, IRA, POTTER, MICHAEL
Zdroj: Nature; February 1975, Vol. 253 Issue: 5492 p550-552, 3p
Abstrakt: MOST murine lymphomas induced by commonly available murine leukaemia viruses (such as Gross passage A and Moloney leukaemia viruses) arise in the thymus1, originating as thymocytes or thymus-derived (T) cells. The tumours thus usually carry the surface θ antigen2, they rarely have B-cell surface markers such as the κ (light) chain. Abelson and Rabstein, however, reported a leukaemia virus that induces non-thymic lymphomas3–5, which we have now found to have surface κ chains under certain circumstances.
Databáze: Supplemental Index